Awesome! Those lymphocytes that recognize MHC pass the positive selection test in the cortex and move onto the negative selection (clonal deletion) test in the medulla.

mm-negative-selection.png

What is negative selection?

Histo Scavenger Hunt!

Take a snapshot of a thymic (Hassall’s) corpuscle in the medulla, from Slide 76: Thymus, H&E.

Normally the thymus involutes with age.

Compare Slide 123 Thymus, H&E and Slide 126 Thymus, H&E, then describe what occurs during involution of an organ.

MM-Pg6-Slide123.png

MM-Pg6-Slide126.png

The results from a blood test that you ordered are in.

Go check-in with your patient.